Basaglar (insulin glargine) approved in 2015 is a “follow-on” insulin to Lantus, and Admelog (insulin lispro) was approved as a “follow on” for Humalog in 2017. A “follow on” insulin (also called a biosimilar in other countries beside the U.S.) are approved via an abbreviated FDA process (the 505(b)(2) pathway) in which the manufacturer demonstrates that the “add-on” product is as safe and effective as the original insulin. These insulins have the same active ingredients, but cannot be substituted for each other at the pharmacy without your doctor’s approval. The new follow on insulins may only save you a little at the pharmacy compared to the original brands, but check the manufacturers website for both all products to determine cost savings.
Jump up ^ Lo HC, Tu ST, Lin KC, Lin SC (2004). “The anti-hyperglycemic activity of the fruiting body of Cordyceps in diabetic rats induced by nicotinamide and streptozotocin”. Life Sciences. 74 (23): 2897–908. doi:10.1016/j.lfs.2003.11.003. PMID 15050427.
Am I at risk for type 2 diabetes? Taking steps to lower your risk of getting diabetes. (2012, June). Retrieved from http://www.niddk.nih.gov/health-information/health-topics/Diabetes/type-2-diabetes-taking-steps-lower-your-risk-diabetes/Pages/index.aspx.
Some people with diabetes use a computerized pump — called an insulin pump — that gives insulin on a set basis. You and your doctor program the pump to deliver a certain amount of insulin throughout the day (the basal dose). Plus, you program the pump to deliver a certain amount of insulin based on your blood sugar level before you eat (bolus dose).
You might be wondering about how exercise will affect your diabetes, but you shouldn’t use diabetes as an excuse not to get moving. Most types of exercise are great for people with type 2 diabetes — from walking the dog or riding a bike to playing team sports. Make it your goal to exercise every day to get the most benefits.
Exercise is also an important part of diabetes treatment. Regular physical activity helps keep blood sugar levels in a healthy range. It also can reduce the risk of other health problems that people with diabetes may be more likely to get, like heart disease.
Polycystic ovary syndrome (PCOS): This is a common cause of female infertility and insulin resistance. It can cause signs and symptoms like irregular periods, acne, thinning scalp hair, and excess hair growth on the face and body. High insulin levels also increase the risk of developing diabetes, and about half of women with PCOS develop diabetes.
Type 1 diabetes is thought to be caused by inherited and environmental risk factors. In Type 1, which is often diagnosed in autoimmune beta-cell destruction in the pancreas leads to absolute insulin deficiency. Prediabetes and type 2 diabetes also appear to be linked to genetic and environmental risk factors, as well as lifestyle issues such as being overweight or obese. In Type 2 diabetes, progressive loss of beta-cell insulin secretion combined with insulin resistance leads to disease. If caught early enough with screening, and combined with appropriate diet, exercise, and lifestyle changes, prediabetes can be reversible. In the U.S., being overweight or obese is the most common modifiable risk factor for type 2 diabetes; however, not all patients with type 2 diabetes have weight problems.
Unhealthy fats include trans fats and the overconsumption of saturated fats, which can increase your risk of heart disease. Found in red meats, full-fat dairy products, and baked goods, these fats can cause LDL (bad) cholesterol and triglyceride levels to go up.
Many research studies have shown that meals which contain sugar do not make the blood sugar rise higher than meals of equal carbohydrate levels which do not contain sugar. However, if the sugar-containing meal contains more carbs, the blood sugar levels will go up.
Yet understanding what and how much to eat can be a challenge. A registered dietitian can help you create a meal plan that fits your health goals, food preferences and lifestyle. This will likely include carbohydrate counting, especially if you have type 1 diabetes.
See Section 12 for recommendations specific for children and adolescents with type 2 diabetes. The use of metformin as first-line therapy was supported by findings from a large meta-analysis, with selection of second-line therapies based on patient-specific considerations (30). An ADA/European Association for the Study of Diabetes position statement “Management of Hyperglycemia in Type 2 Diabetes, 2015: A Patient-Centered Approach” (31) recommended a patient-centered approach, including assessment of efficacy, hypoglycemia risk, impact on weight, side effects, costs, and patient preferences. Renal effects may also be considered when selecting glucose-lowering medications for individual patients. Lifestyle modifications that improve health (see Section 4 “Lifestyle Management”) should be emphasized along with any pharmacologic therapy.
Most checkups will involve blood sugar testing, even if the person has no symptoms. The U.S. Preventive Services Task Force recommend that adults age 40 to 70 who are overweight should be tested for diabetes. Those who have a family history of diabetes or who have other risk factors may need earlier or more frequent tests.
Diabetes (diabetes mellitus) is classed as a metabolism disorder. Metabolism refers to the way our bodies use digested food for energy and growth. Most of what we eat is broken down into glucose. Glucose is a form of sugar in the blood – it is the principal source of fuel for our bodies.
Why? Normally your body reabsorbs glucose as it passes through your kidneys. But when diabetes pushes your blood sugar up, your kidneys may not be able to bring it all back in. This causes the body to make more urine, and that takes fluids.
There’s nothing more comforting than a warm bowl of oatmeal in the morning. Plus, it’s a more nutritious option than many other starchy breakfast foods, such as sugary cereals, sweet rolls, and bagels, according to the American Diabetes Association (ADA). Also, because of its fiber content (2 grams fiber in a 1/2-cup serving of cooked oatmeal), it gives you more staying power than low-fiber options.
Jump up ^ Buehler AM; Cavalcanti AB; Berwanger O; et al. (June 2013). “Effect of tight blood glucose control versus conventional control in patients with type 2 diabetes mellitus: a systematic review with meta-analysis of randomized controlled trials”. Cardiovasc Ther. 31 (3): 147–60. doi:10.1111/j.1755-5922.2011.00308.x. PMID 22212499.
The classic symptoms of untreated diabetes are weight loss, polyuria (increased urination), polydipsia (increased thirst), and polyphagia (increased hunger). Symptoms may develop rapidly (weeks or months) in type 1 DM, while they usually develop much more slowly and may be subtle or absent in type 2 DM.
In the United Kingdom Prospective Diabetes Study (UKPDS), researchers followed nearly 4,000 people with type 2 diabetes for 10 years. The study monitored how tight control of blood glucose (HbA1c of 7% or less) and blood pressure (less than 144 over less than 82) could protect a person from the long-term complications of diabetes.
An international expert committee of the American Diabetes Association redefined the criteria for prediabetes, lowering the blood sugar level cut-off point for prediabetes. Approximately 20% more adults are now believed to have this condition and may develop diabetes within 10 years unless they change to healthier lifestyles, such as exercising more and maintaining a healthy weight.
Jump up ^ Tupola, S; Rajantie, J; Mäenpää, J (1998). “Severe hypoglycaemia in children and adolescents during multiple-dose insulin therapy”. Diabetic medicine. 15 (8): 695–69. doi:10.1002/(SICI)1096-9136(199808)15:8<695::AID-DIA651>3.0.CO;2-C. PMID 9702475.
That’s doubly true if you’re middle-aged or older. The fall in estrogen levels associated with menopause can make it difficult for a woman’s body to maintain healthy blood sugar levels, which can increase her risk for diabetes, says Leanne Redman, PhD, an associate professor of endocrinology and women’s health at Louisiana State University’s Pennington Biomedical Research Center (PBRC).
The incidences of type 1 diabetes and type 2 diabetes are increasing rapidly. This is due to many factors, but the most significant reasons for type 2 diabetes are the increasing incidence of obesity associated with sedentary lifestyles.
Another plus for asparagus is its folate content — a 1/2-cup serving, or about six 1/2-inch spears, provides 33 percent of the 400 micrograms of folate recommended daily. The American Heart Association advises eating foods containing folate and other B vitamins to help lower homocysteine levels, a risk factor for coronary heart disease.
So how do blood glucose levels relate to type 2 diabetes? People with type 2 diabetes don’t respond normally to insulin anymore, so glucose stays in the bloodstream and doesn’t get into the cells. This causes blood glucose levels to go too high.
One way to approach diabetes is to use integrative holistic medicine, also known as alternative medicine, a medical specialty that focuses on caring for the whole person, treating and preventing disease, and empowering patients to create conditions for optimal health, according to the American Board of Integrative Holistic Medicine.